双波长比值光谱法测定复方益康宁片二组分的含量

               作者：黄喜茹，刘伟娜，周亚君，曹冬

【关键词】  双波长比值光谱法

    Dualwavelength  ratio  spectrophotometry  for determination of procaine hydrochloride and vitamin B6 in compound Yikangning  tablets

　　【Abstract】 AIM: To establish dual-wavelength ratio spectrophotometry for determination of  procaine hydrochloride and vitamin B6 in compound Yikangning tablets.  METHODS: The ratio spectra was determined and the wavelength pair were selected at the peak point or valley point of ratio spectra , to eliminate the interference of other components.  RESULTS:  Linearity between the absorbance and concentration of  procaine  hydrochloride and vitamin B6 was obtained in the range of 5.0-50.0 mg/L under the optimum conditions . The average recoveries and relative standard deviations(RSD) of procaine  hydrochloride and vitamin B6 were 99.5%, 1.2% and  98.3%, 0.8%, respectively. CONCLUSION: The method  was simple , rapid and reproducible ,  the interference  of  two components on each other may be eliminated and the results were satisfactory.

　　【Keywords】 dualwavelength ratio spectrophotometry; procaine hydrochloride; vitamin B6; Yikangning tablet

　　【摘要】 目的：建立复方益康宁片中盐酸普鲁卡因和维生素B6的双波长比值光谱测定法. 方法：绘制盐酸普鲁卡因和维生素B6的比值光谱，选择其峰点或谷点作为测定波长对有效地消除共存组分的干扰，以实现对被测组分的准确测定. 结果：在选定的实验条件下，盐酸普鲁卡因和维生素B6在5.0～50.0 mg/L范围线性关系良好，平均回收率分别为99.5%, 98.3%和相对标准偏差(RSD)分别为1.2%, 0.8%. 结论：该方法

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