广州地区A组链球菌T分型的分布状况

　　【摘要】目的　研究广州地区风湿热易感自然人群A组链球菌（GAS）T型的分布状况。方法从1990年5月至1991年4月，对广州地区9～14岁学龄儿童共453名（城市250名，农村203名）每月取咽拭子培养1次，分离β-溶血性链球菌后，采用兰菲分组鉴定出GAS共732株，对GAS采用凝集法进行T分型。结果　广州市学龄儿童携带的GAS的T型以T6(20.5%)、T4(12.0%)、T12(10.9%)多见。T型分布无性别差异(P＞0.05)，但有季节差异。同一学校不同班级有不同的 T型分布。不可分型菌株占13.3%。结论　1990～1991年广州地区学龄儿童流行GAS的T型主要以T6、4、12为多见；不同时期和不同地区流行GAS的T型分布存在差异。

　　Epidemic trends of T-typing of group A streptococci in guangzhou area

　　 【Abstract】Objective　To investigate the epidemic trends of the T typing of group A hemolytic streptococci (GAS) isolated from Guangzhou school children in China from 1990 to 1991.Methods　732 group A streptococci were isolated from throat culture of 453 school children aged 9～14 years in Guangzhou City, South China from May 1990 to April 1991. Their T-type detection rates, T-type epidemics, monthly isolation rates, and isolation rates by sex were analysed epidemiologically.Results　Among the children, the most common serotype was T6 (20.5%),followed by T4(12.0%), and T12 (10.9%). The main serotype in Guangzhou urban areas was T6 (30.6%), and in the rural areas was  ;T12 (21.0%). There was statistically significant difference (P＜0.005) between urban and rural areas. There was no significant difference between male and female, but quite difference in different seasons. Different class in the same school had different T serotype distribution. Non-typable strains reached 13.3%.Conclusion　The dominant prevalent strains of GAS were T6, 4, 12 in Guangzhou school children， South China from 1990 to 1991. The distribution of GA

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